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Normal saline resuscitation worsens lactic acidosis in experimental sepsis

Zhou, Feihu and Cove, Matthew E and Peng, Zhiyong Y and Bishop, Jeffrey and Singbartl, Kia and Kellum, John A. (2012) Normal saline resuscitation worsens lactic acidosis in experimental sepsis. In: 32nd International Symposium on Intensive Care and Emergency Medicine (ISICEM) 2012, 20 March 2012 - 23 March 2012, Brussels, Belgium.

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Abstract

It is well established that infusing large amounts of normal saline causes hyperchloremic acidosis, yet the clinical relevance of this is unknown. We found that infusion of normal saline, compared with a balanced crystalloid, worsens lactic acidosis in experimental sepsis.


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Details

Item Type: Conference or Workshop Item (Poster)
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Zhou, Feihu
Cove, Matthew E
Peng, Zhiyong Y
Bishop, Jeffrey
Singbartl, Kia
Kellum, John A.kellum@pitt.eduKELLUM0000-0003-1995-2653
Date: 19 April 2012
Date Type: Publication
Journal or Publication Title: F1000 Research
Publisher: F1000 Research Ltd.
Event Title: 32nd International Symposium on Intensive Care and Emergency Medicine (ISICEM) 2012
Event Dates: 20 March 2012 - 23 March 2012
Event Type: Conference
Schools and Programs: School of Medicine > Critical Care Medicine
Refereed: No
ISSN: 2046-1402
Official URL: https://f1000research.com/posters/1090064
Additional Information: Funding: National Institutes of Health (NIH), HL07820 Competing Interests: No competing interests were disclosed
Date Deposited: 29 Nov 2016 17:07
Last Modified: 01 Nov 2017 14:01
URI: http://d-scholarship.pitt.edu/id/eprint/30134

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