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Emerging waves of carbapenem resistance among gram negative pathogens at a tertiary center

Paronish, Julie (2016) Emerging waves of carbapenem resistance among gram negative pathogens at a tertiary center. Master Essay, University of Pittsburgh.

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Abstract

Carbapenem resistant organisms (CROs) have emerged as a public health crisis because of high rates of mortality and morbidity. Epidemiologic and clinical factors contributing to patient outcomes vary. Objectives included evaluating emergence of CROs, and identifying factors associated with patient mortality at UPMC Presbyterian hospital. Microbiology records were extracted from the most common gram-negative pathogens, E.coli(Ecol), Klebsiella pneumoniae(Klpn), Pseudomonas aeruginosa(Psar), Enterobacter aerogenes/cloacae(Entb), Serratia marcescens(Serm), and Acinetobacter baumannii(Acat) from 2000-2015. We identified 84,597 isolates from 37,823 patients. Among all isolates 9.5% (8,864) were classified as CROs. Standardized by patient, 7.5% of isolates were CR in 2000, 14.6% in 2015 (P


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Details

Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Unpublished
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Paronish, Juliejup46@pitt.eduJUP46
Contributors:
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairGlynn, Nancy W.glynnn@edc.pitt.eduUNSPECIFIEDUNSPECIFIED
Committee MemberShields, Ryan K.rshieres@pitt.eduUNSPECIFIEDUNSPECIFIED
Committee MemberMartinson, Jeremy J.jmartins@pitt.eduUNSPECIFIEDUNSPECIFIED
Date: 21 November 2016
Date Type: Publication
Publisher: University of Pittsburgh
Institution: University of Pittsburgh
Schools and Programs: Graduate School of Public Health > Epidemiology
Degree: MPH - Master of Public Health
Thesis Type: Master Essay
Refereed: Yes
Date Deposited: 23 May 2017 18:00
Last Modified: 05 Sep 2017 22:55
URI: http://d-scholarship.pitt.edu/id/eprint/30350

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