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SKIN-INSPIRED HYDROGEL-ELASTOMER COMPOSITE WITH APPLICATOIN IN A MOISTURE PERMEABLE PROSTHETIC LIMB LINER

Ruiz, Esteban (2017) SKIN-INSPIRED HYDROGEL-ELASTOMER COMPOSITE WITH APPLICATOIN IN A MOISTURE PERMEABLE PROSTHETIC LIMB LINER. Doctoral Dissertation, University of Pittsburgh. (Unpublished)

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Abstract

Recent advances in fields such as 3D printing, and biomaterials, have enabled the development of a moisture permeable prosthetic liner. This project demonstrates the feasibility of the invention by addressing the three primary areas of risk including the mechanical strength, the permeability, and the ability to manufacture. The key enabling technology which allows the liner to operate is the skin inspired hydrogel elastomer composite. The skin inspiration is reflected in the molecular arrangement of the double network of polymers which mimics collagen-elastin toughening in the natural epidermis. A custom formulation for a novel tough double network nanocomposite reinforced hydrogel was developed to improve manufacturability of the liner. The liner features this double network nanocomposite reinforced hydrogel as a permeable membrane which is reinforced on either side by perforated silicone layers manufactured by 3d printing assisted casting. Uniaxial compression tests were conducted on the individual hydrogels, as well as a representative sample of off the shelf prosthetic liners for comparison. Permeability testing was also done on the same set of materials and compared to literature values for traditional hydrogels. This work led to the manufacture of three generations of liner prototypes, with the second and third liner prototype being tested with human participants.


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Details

Item Type: University of Pittsburgh ETD
Status: Unpublished
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Ruiz, Estebanesr26@pitt.eduesr260000-0002-5817-5984
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairBrienza, Daviddbrienza@pitt.edudbrienza
Committee MemberPeterson, Saraspeterso@pitt.eduspeterso
Committee MemberBeckman, Ericbeckman@pitt.edubeckman
Committee MemberKarg, Patricatkarg@pitt.edutkarg
Committee MemberPearlman, Jonathanjpearlman@pitt.edujpearlman
Date: 5 June 2017
Date Type: Publication
Defense Date: 30 March 2017
Approval Date: 5 June 2017
Submission Date: 17 April 2017
Access Restriction: 2 year -- Restrict access to University of Pittsburgh for a period of 2 years.
Number of Pages: 138
Institution: University of Pittsburgh
Schools and Programs: School of Health and Rehabilitation Sciences > Rehabilitation Science
Degree: PhD - Doctor of Philosophy
Thesis Type: Doctoral Dissertation
Refereed: Yes
Uncontrolled Keywords: hydrogel prosthetic limb liner
Date Deposited: 05 Jun 2017 17:18
Last Modified: 05 Jun 2019 05:15
URI: http://d-scholarship.pitt.edu/id/eprint/31590

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  • SKIN-INSPIRED HYDROGEL-ELASTOMER COMPOSITE WITH APPLICATOIN IN A MOISTURE PERMEABLE PROSTHETIC LIMB LINER. (deposited 05 Jun 2017 17:18) [Currently Displayed]

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