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Evaluation of a Combination Allograft Material Compared to DFDBA in Alveolar Ridge Preservation

Jose, Sanju (2017) Evaluation of a Combination Allograft Material Compared to DFDBA in Alveolar Ridge Preservation. Master's Thesis, University of Pittsburgh. (Unpublished)

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Purpose: The aim of this split-mouth clinical study was to compare DFDBA to a combination allograft that is 70% FDBA and 30% DFDBA, in alveolar ridge preservation. Changes in ridge dimension were evaluated, as was graft consolidation, ability to place implants, and additional grafting needs.
Materials and methods: 20 extraction sockets in 6 patients (3 males, 3 females) who presented to the School of Dental Medicine were selected to be part of the study. These patients required 20 extractions with ridge preservation, with the eventual goal of being restored with dental implants. Extraction sockets were randomly assigned to either the control group (DFDBA) or the test group (combination allograft). Immediately after extraction, a limited CBCT was taken to evaluate the socket. Following the scan, the extraction sockets received the assigned graft material, was covered with fast absorbing collagen dressing, and sutured with polyglactin. After 6 months, a second scan was taken. 3-D rending software was used to compare the two scans and measure horizontal dimensional changes to the ridge. CBCT sections were also used to evaluate graft integration. Ability to place implants and additional grafting needs at the time of implant placement was also noted.
Results: Despite our best efforts to preserve the ridge, some dimensional change is bound to occur. This change was found as a loss of 0.67 mm for the test group and 0.74 mm for the control group. Graft integration was excellent for both the control and test groups. Implant placement was possible without any additional augmentation in these sites that underwent alveolar ridge preservation.
Conclusion: Extraction followed by alveolar ridge preservation using either demineralized freeze-dried bone allograft or a 70:30 combination allograft resulted in minimal and clinically negligible changes in alveolar ridge dimensions. It can also be concluded that there were minimal and clinically negligible differences between the two grafting materials when measuring changes in alveolar ridge dimensions. CBCT scans showed excellent graft integration for both materials, and implants were placed in sites grafted with both materials without any need for additional augmentation. These findings need to be confirmed with a larger sample.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Jose, Sanjusaj80@pitt.edusaj80
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairFamili, Pouranpof@pitt.edupof
Committee MemberPotluri, Anithaanp60@pitt.eduanp60
Committee MemberBaumhammers, Andrejsanb3@pitt.eduanb3
Date: 9 June 2017
Date Type: Publication
Defense Date: 9 June 2017
Approval Date: 9 June 2017
Submission Date: 9 June 2017
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Number of Pages: 36
Institution: University of Pittsburgh
Schools and Programs: School of Dental Medicine > Dental Science
Degree: MDS - Master of Dental Science
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: combination allograft
Date Deposited: 09 Jun 2017 20:00
Last Modified: 09 Jun 2017 20:00


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