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Kinematics of the Anterior Cruciate Ligament (ACL) and ACL Graft

Zhu, Junjun (2018) Kinematics of the Anterior Cruciate Ligament (ACL) and ACL Graft. Doctoral Dissertation, University of Pittsburgh. (Unpublished)

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The anterior cruciate ligament (ACL) is one of the four main ligaments of the knee and is the most important ligament for knee’s stability. ACL injury has an annual incidence of more than 200,000 cases with approximately 100,000 of these knees having ACL reconstruction annually in the United States alone. However, the behaviors of the ACL and the graft in knees were still debated. There is still no golden standard in choosing appropriate reconstruction techniques, such as the position and orientation of the graft. Tunnel enlargement, and graft failure could happen after reconstruction if the ACL graft was improperly placed. To have better knowledge of the behavior of the intact ACL during flexion-extension and under external loads, this dissertation measured the strain of two bundles of the ACL by using two different measurement methods. This dissertation also measured graft position in the femoral tunnel during knee motions and under different external loadings. This graft position information provides insight into ACL graft behavior and function and may be important for determining appropriate rehabilitation time. Last, a finite element (FE) model was constructed and used to simulate the graft behavior in reconstructed knees with boundary and loading conditions from corresponding cadaveric experiments. The geometry of the tibia and femur were obtained from CT imaging. An isotropic hyperelastic material was used to model the cylindrical graft. Three-dimensional joint kinematics were obtained via a six-degree-of-freedom robotic manipulator and were used for input into the computational model. Graft stress, tension as well as the location of the graft in the tunnel were calculated after the kinematics were applied.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Zhu, Junjunjuz18@pitt.edujuz18
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairSmolinski, Patrick
Committee MemberWang, Qing-Ming
Committee MemberMiller, Mark
Committee MemberSlaughter, William
Date: 20 June 2018
Date Type: Publication
Defense Date: 11 December 2017
Approval Date: 20 June 2018
Submission Date: 28 March 2018
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Number of Pages: 175
Institution: University of Pittsburgh
Schools and Programs: Swanson School of Engineering > Mechanical Engineering
Degree: PhD - Doctor of Philosophy
Thesis Type: Doctoral Dissertation
Refereed: Yes
Uncontrolled Keywords: ACL, Finite Element, Soft tissue
Date Deposited: 20 Jun 2018 18:42
Last Modified: 20 Jun 2018 18:42


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