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The effect of Eck and reverse Eck fistula in dogs with experimental diabetes mellitus

Meyer, WH and Starzl, TE (1959) The effect of Eck and reverse Eck fistula in dogs with experimental diabetes mellitus. Surgery, 45 (5). 760 - 764. ISSN 0039-6060

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Abstract

1. 1. Dogs with alloxan diabetes were subjected to Eck fistula. This procedure produced a marked increase in the amount of insulin necessary to control glycosuria. When the dogs were fasted, glycosuria disappeared, blood sugars fell toward normal, and the need for insulin was eliminated. 2. 2. Reverse Eck fistula was created in dogs with alloxan diabetes, and resulted in minor increases of doubtful significance in daily insulin requirement. When fasted, the blood sugar of these animals remained elevated and glycosuria continued. 3. 3. Nondiabetic dogs with Eck fistula all died of meat intoxication. Dogs with Eck fistula plus diabetes had no evidence of meat intoxication and in general were in better health than dogs with Eck fistula alone. 4. 4. Possible mechanisms of the role of Eck fistula in the alteration of the diabetic state are discussed. © 1959.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Meyer, WH
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 May 1959
Date Type: Publication
Journal or Publication Title: Surgery
Volume: 45
Number: 5
Page Range: 760 - 764
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0039-6060
Other ID: uls-drl:31735062123389, Starzl CV No. 17
Date Deposited: 08 Apr 2010 16:59
Last Modified: 05 Dec 2017 17:01
URI: http://d-scholarship.pitt.edu/id/eprint/3403

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