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Histopathologic alterations associated with the transplanted homologous dog liver

Brock, DR and Starzl, TE (1962) Histopathologic alterations associated with the transplanted homologous dog liver. Experimental and Molecular Pathology, 1 (3). 187 - 203. ISSN 0014-4800

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Abstract

Homotransplanted livers in dogs developed mononuclear, lymphocytic and plasmacytic infiltration and hepatic cell degeneration roughly paralleling survival time. Extensive histologic alterations of host reticuloendothelial structures occurred. Proliferation and infiltration of mononuclear cells, principally plasmacytes, were noted in lung, kidney, perirenal supportive tissue, bone marrow, and lymph nodes. Lymph nodes, in addition, were characterized by cortical and follicular depletion. These changes were considered to represent extensive host reticuloendothelial mobilization coincident to liver homotransplant rejection. The relation between these alterations and those found in other hypersensitivity states is discussed. © 1962.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Brock, DR
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1962
Date Type: Publication
Journal or Publication Title: Experimental and Molecular Pathology
Volume: 1
Number: 3
Page Range: 187 - 203
DOI or Unique Handle: 10.1016/0014-4800(62)90020-5
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0014-4800
Other ID: uls-drl:31735062123363, Starzl CV No. 50
Date Deposited: 08 Apr 2010 16:59
Last Modified: 02 Feb 2019 13:58
URI: http://d-scholarship.pitt.edu/id/eprint/3436

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