Starzl, TE and Marchioro, TL and Talmage, DW and Waddell, WR
(1963)
Splenectomy and Thymectomy in Human Renal Homotransplantation.
Proceedings of the Society for Experimental Biology and Medicine, 113 (4).
929 - 932.
ISSN 0037-9727
Abstract
Five patients with terminal renal failure have been treated with renal homografts. Total body irradiation and cytotoxic drugs were used to prevent rejection. In addition, the thymus and spleen were surgically removed prior to the homotransplantation. Four of the 5 patients are alive with good renal function after 105 to 198 days. The role of thymectomy and splenectomy in conditioning patients for the receipt of homografts is highly speculative at present. However, the early success rate in this group of patients exceeds that generally attained with renal homografts, and appears to justify further clinical evaluation of this approach under carefully controlled experimental conditions. The data are insufficient to allow a recommendation for the general use of these adjuvant procedures. © 1963, SAGE Publications. All rights reserved.
Share
| Citation/Export: |
|
| Social Networking: |
|
Details
Metrics
Monthly Views for the past 3 years
Plum Analytics
Altmetric.com
Actions (login required)
 |
View Item |
![[img]](https://d-scholarship.pitt.edu/style/images/fileicons/text_plain.png)
![[feed]](/images/feed-icon-32x32.png){kind=icon}