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The clinical use of antilymphocyte globulin in renal homotransplantation

Starzl, TE and Marchioro, TL and Hutchison, DE and Porter, KA and Cerilli, GJ and Brettschneider, L (1967) The clinical use of antilymphocyte globulin in renal homotransplantation. Transplantation, 5 (4). 1100 - 1105. ISSN 0041-1337

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Twenty patients were treated with antilymphocyte globulin (ALG) which was prepared from the serum of immunized horses. The ALG was used as an adjuvant to azathioprine and prednisone and its use limited to 4 months. The surviving patients are now 1 to 7 months postoperative. There was 1 death, the consequence of a technical accident. The function in the remaining 19 patients is excellent, despite reduced doses of azathioprine and especially prednisone. Biopsies were obtained in the first 8 consecutive cases from 108 to 145 days after operation. There was no evidence in the specimens of either Masugi-like or serum sickness nephritis. © 1967 by The Williams and Wilkins Co.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Starzl, TEtes11@pitt.eduTES11
Marchioro, TL
Hutchison, DE
Porter, KA
Cerilli, GJ
Brettschneider, L
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1967
Date Type: Publication
Journal or Publication Title: Transplantation
Volume: 5
Number: 4
Page Range: 1100 - 1105
DOI or Unique Handle: 10.1097/00007890-196707001-00045
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0041-1337
Other ID: uls-drl:31735062124593, Starzl CV No. 137
Date Deposited: 08 Apr 2010 17:01
Last Modified: 16 Aug 2020 09:55


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