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Hypernatremia: Complication of Renal Homotransplantation

Popovtzer, MM and Pinggera, WF and Holmes, JH and Halgrimson, CG and Starzl, TE (1971) Hypernatremia: Complication of Renal Homotransplantation. Archives of Internal Medicine, 127 (6). 1129 - 1132. ISSN 0003-9926

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Hypernatremia was observed in five recipients of renal homografts during the first postoperative week. The peak serum levels of sodium varied between 152 and 158 mEq/liter. The postoperative diuresis was associated with sodium concentration in the urine, consistently lower than that in the extracellular water; moderate urinary hypertonicity, with urea being the main urinary solute; and urea excretion exceeding 60% of its filtered load in most instances. The inability of elaborate urine with sodium concentration equal or higher than that in the serum, possibly related to osmotic diuresis and/or altered renal hemodynamics, appears to be the primary cause responsible for the development of hypernatremia in these patients. © 1971, American Medical Association. All rights reserved.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Popovtzer, MM
Pinggera, WF
Holmes, JH
Halgrimson, CG
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1971
Date Type: Publication
Journal or Publication Title: Archives of Internal Medicine
Volume: 127
Number: 6
Page Range: 1129 - 1132
DOI or Unique Handle: 10.1001/archinte.1971.00310180145020
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0003-9926
Other ID: uls-drl:31735062127885, Starzl CV No. 216
Date Deposited: 08 Apr 2010 17:03
Last Modified: 02 Feb 2019 13:57


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