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ORTHOTOPIC LIVER TRANSPLANTATION FOR WILSON'S DISEASE

Dubois, RS and Rodgerson, DO and Martineau, G and Shroter, G and Giles, G and Lilly, J and Halgrimson, CG and Starzl, TE and Sternlieb, I and Scheinberg, IH (1971) ORTHOTOPIC LIVER TRANSPLANTATION FOR WILSON'S DISEASE. The Lancet, 297 (7698). 505 - 508. ISSN 0140-6736

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Abstract

An 11-year-old boy with terminal hepatic failure due to Wilson's disease was treated 18 months ago with orthotopic liver transplantation. Postoperatively, there has been evidence of clearance of body copper stores but without accumulation of copper in biopsy specimens of the transplanted liver after 6 and 17 months. Further follow-up will be necessary before deciding whether the disorder has been cured by liver replacement and in turn whether this constitutes proof that Wilson's disease is an inborn error of hepatic metabolism. The observations so far are consistent with these conclusions. © 1971.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Dubois, RS
Rodgerson, DO
Martineau, G
Shroter, G
Giles, G
Lilly, J
Halgrimson, CG
Starzl, TEtes11@pitt.eduTES11
Sternlieb, I
Scheinberg, IH
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 13 March 1971
Date Type: Publication
Journal or Publication Title: The Lancet
Volume: 297
Number: 7698
Page Range: 505 - 508
DOI or Unique Handle: 10.1016/s0140-6736(71)91121-4
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0140-6736
Other ID: uls-drl:31735062108505, Starzl CV No. 247
PubMed ID: 4100432
Date Deposited: 08 Apr 2010 17:04
Last Modified: 23 Jun 2018 11:55
URI: http://d-scholarship.pitt.edu/id/eprint/3633

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