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Delayed biliary duet obstruction after orthotopic liver transplantation

Martineau, G and Porter, KA and Corman, J and Launois, B and Schroter, GT and Palmer, W and Putnam, CW and Groth, CG and Halgrimson, CG and Penn, I and Starzl, TE (1972) Delayed biliary duet obstruction after orthotopic liver transplantation. Surgery, 72 (4). 604 - 610. ISSN 0039-6060

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After orthotopic liver transplantation and biliary reconstruction by cholecystoduodenostomy, four of 40 patients developed delayed obstruction of the cystic duct. The recipients had the clinical syndrome of fulminating cholangitis with jaundice, fever, leukocytosis, toxemia, and bacteremia. All four patients died; of the four, two patients died despite late reoperation and re-establishment of bile drainage by choledochoenterostomy. In all four cases, a factor contributing to the biliary obstruction may have been infection of the extrahepatic biliary ducts with or without ulceration, and in three of the livers, there was evidence of infection of the ducts with CMV. If cholecystoduodenostomy is used in future cases, prompt re-exploration and conversion to choledochoenterostomy should be considered if the diagnosis of duct obstruction, cholangitis, and persistent bacteremia are made. © 1972.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Martineau, G
Porter, KA
Corman, J
Launois, B
Schroter, GT
Palmer, W
Putnam, CW
Groth, CG
Halgrimson, CG
Penn, I
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1972
Date Type: Publication
Journal or Publication Title: Surgery
Volume: 72
Number: 4
Page Range: 604 - 610
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0039-6060
Other ID: uls-drl:31735062108778, Starzl CV No. 272
Date Deposited: 08 Apr 2010 17:04
Last Modified: 02 Feb 2019 13:55


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