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Variations in Arterial Blood Pressure after Kidney Transplantation

POPOVTZER, MORDECAI M and PINNGGERA, WULF and KATZ, FRED H and CORMAN, JACQUES L and ROBINETTE, JOHN and LANOIS, BERNARD and HALGRIMSON, CHARLES G and STARZL, THOMAS E (1973) Variations in Arterial Blood Pressure after Kidney Transplantation. Circulation, 47 (6). 1297 - 1305. ISSN 0009-7322

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Abstract

<jats:p>The course of hypertension within the first 2 months after kidney transplantation was correlated with renal function, plasma renin activity (PRA), and the daily maintenance dose of prednisone in 18 homograft recipients. During acute rejection blood pressure (BP) closely correlated with PRA. Patients with normal homograft function showed an increase in BP early after transplantation which in most returned to normal 3-8 weeks later. In the latter group no correlation could be found between the level of BP and PRA, however the BP correlated closely with the dose of prednisone. These observations suggest that during acute rejection the increase in BP may at least partly be mediated by a renal pressor mechanism, whereas with normal renal function the high dose of glucocorticoids may play an important role in the development of hypertension.</jats:p>


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
POPOVTZER, MORDECAI M
PINNGGERA, WULF
KATZ, FRED H
CORMAN, JACQUES L
ROBINETTE, JOHN
LANOIS, BERNARD
HALGRIMSON, CHARLES G
STARZL, THOMAS Etes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: June 1973
Date Type: Publication
Journal or Publication Title: Circulation
Volume: 47
Number: 6
Publisher: Ovid Technologies (Wolters Kluwer Health)
Page Range: 1297 - 1305
DOI or Unique Handle: 10.1161/01.cir.47.6.1297
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0009-7322
Other ID: uls-drl:31735062109248, Starzl CV No. 319
Date Deposited: 08 Apr 2010 17:05
Last Modified: 11 Jul 2021 14:55
URI: http://d-scholarship.pitt.edu/id/eprint/3705

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