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Transplantation in children

Weil, R and Putnam, CW and Porter, KA and Starzl, TE (1976) Transplantation in children. Surgical Clinics of North America, 56 (2). 467 - 476. ISSN 0039-6109

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Kidney transplantation in very young children, less than 2 years of age, has usually failed, mainly because of difficulties maintaining these patients on hemodialysis long enough to permit retransplantation after loss of the original graft. Liver replacement in the very young child has been associated with a higher frequency of vascular and biliary obstruction than in the older child, due to the small size of these structures. Such accidents have contributed to unsatisfactory results with biliary atresia. Transplantation of kidney or liver into older children has been more successful than transplantation of these organs into adults. Related or cadaveric kidney transplantation in the child has been followed by at least a 60 per cent patient survival for 6 to 13 years and a very acceptable quality of life. Liver replacement for diseases other than biliary atresia has been followed by a 56 per cent 1 year survival rate, and two children have survived for more than 5 years.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Weil, R
Putnam, CW
Porter, KA
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1976
Date Type: Publication
Journal or Publication Title: Surgical Clinics of North America
Volume: 56
Number: 2
Page Range: 467 - 476
DOI or Unique Handle: 10.1016/s0039-6109(16)40889-3
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0039-6109
Other ID: uls-drl:31735062109677, Starzl CV No. 366
Date Deposited: 08 Apr 2010 17:06
Last Modified: 02 Feb 2019 13:57


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