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Challenges in efforts to control Yellow fever outbreaks in Brazil since 2016: a literature review

Owens, Elizabeth (2019) Challenges in efforts to control Yellow fever outbreaks in Brazil since 2016: a literature review. Master Essay, University of Pittsburgh.

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Yellow fever is a vector-borne disease transmitted to humans and non-human primates through the bite of an infected mosquito. The disease is preventable with a live-attenuated vaccine, which is considered safe, effective, and provides lifelong immunity. Since 2016, Brazil has experienced an influx of Yellow fever outbreaks throughout the country due to the expansion of the virus. This literature review examines factors contributing to the expansion of Yellow fever throughout Brazil and identifies challenges to Yellow fever prevention and control efforts ongoing throughout the country. A systematic literature search was conducted, and twenty-nine relevant articles were found to meet the selection criteria of Yellow fever, Brazil, challenges, and population health. This review of literature revealed lack of Yellow fever immunity, adverse effects of vaccination, deforestation, fractional dosing, and various vaccine supply chain challenges to be the leading challenges facing the Yellow fever control efforts in Brazil since 2016. In the interest of public health, these findings are significant because they have shown that initiating additional prevention methods and revising policies in turn could exceedingly end the Yellow fever epidemic in Brazil, while simultaneously reducing morbidity and mortality of this vaccine-preventable disease.


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Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Owens, Elizabethemo33@pitt.eduemo33
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairKrier, Sarahsek29@pitt.eduUNSPECIFIEDUNSPECIFIED
Committee MemberVan Panhuis, Wilbertwav10@pitt.eduUNSPECIFIEDUNSPECIFIED
Date: 11 December 2019
Date Type: Completion
Number of Pages: 53
Institution: University of Pittsburgh
Schools and Programs: School of Public Health > Infectious Diseases and Microbiology
Degree: MPH - Master of Public Health
Thesis Type: Master Essay
Refereed: Yes
Date Deposited: 20 Aug 2020 17:56
Last Modified: 20 Aug 2020 17:56


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