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Determinants of Human Papillomavirus Vaccination Coverage in Young Women Across 76 Countries.

Carpio, Kharlya (2020) Determinants of Human Papillomavirus Vaccination Coverage in Young Women Across 76 Countries. Master's Thesis, University of Pittsburgh.

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Introduction: Human papillomavirus (HPV) vaccination is the most effective prevention measure against cervical cancer and one of the pillars of the World Health Organization’s (WHO) global strategy for the elimination of cervical cancer as a public health problem.
Methods: We examined HPV vaccination coverage rates across 76 countries with HPV vaccination programs in 2018. Countries were grouped according to WHO world region classifications and World Bank income level thresholds. We estimated the odds of inclusion of the HPV vaccine into national immunization schedules based on income and region. Regression analysis was used to identify factors that were informative of HPV vaccination coverage.
Results: Developing countries were less likely to have implemented an HPV vaccination program compared to high-income countries (OR: 0.15, 95% CI: 0.08 – 0.31). The existence of a school-based HPV vaccination program was the strongest single factor that explained 43% of the variance in HPV vaccination coverage, taken together with the proportion of women who had received cervical cancer screening in the past three years, and a country’s measles vaccination rate, which was used as proxy to measure the strength of immunization systems.
Conclusions: The full public health potential of HPV vaccination has not yet been achieved. HPV-related cancers continue to be significant sources of worldwide morbidity and mortality, highlighting the need for national HPV vaccination programs with high population coverage.


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Item Type: Other Thesis, Dissertation, or Long Paper (Master's Thesis)
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Carpio, Kharlyakhc16@pitt.edukhc160000-0003-4037-6216
Date: 20 April 2020
Date Type: Submission
Number of Pages: 37
Institution: University of Pittsburgh
Schools and Programs: Graduate School of Public Health > Epidemiology
Degree: MPH - Master of Public Health
Thesis Type: Master's Thesis
Refereed: Yes
Date Deposited: 26 Aug 2020 18:40
Last Modified: 26 Aug 2020 18:40


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