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Accuracy of computerized tomography in determining hepatic tumor size in patients receiving liver transplantation or resection

Mittal, R and Kowal, C and Starzl, T and Van Thiel, D and Bron, K and Iwatsuki, S and Schade, R and Straub, W and Dekker, A (1984) Accuracy of computerized tomography in determining hepatic tumor size in patients receiving liver transplantation or resection. Journal of Clinical Oncology, 2 (6). 637 - 642. ISSN 0732-183X

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Abstract

Computerized tomography (CT) of liver is used in oncologic practice for staging tumors, evaluating response to treatment, and screening patients for hepatic resection. Because of the impact of CT liver scan on major treatment decisions, it is important to assess its accuracy. Patients undergoing liver transplantation or resection provide a unique opportunity to test the accuracy of hepatic-imaging techniques by comparison of finding of preoperative CT scan with those at gross pathologic examination of resected specimens. Forty-one patients who had partial hepatic resection (34 patients) or liver transplantation (eight patients) for malignant (30 patients) or benign (11 patients) tumors were evaluable. Eight (47%) of 17 patients with primary malignant liver tumors, four (31%) of 13 patients with metastatic liver tumors, and two (20%) of 10 patients with benign liver tumors had tumor nodules in resected specimens that were not apparent on preoperative CT studies. These nodules varied in size from 0.1 to 1.6 cm. While 11 of 14 of these nodules were <1.0 cm, three of 14 were >1.0 cm. These results suggest that conventional CT alone may be insufficient to accurately determine the presence or absence of liver metastases, extent of liver involvement, or response of hepatic metastases to treatment.

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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Mittal, R
Kowal, C
Starzl, Ttes11@pitt.eduTES11
Van Thiel, D
Bron, K
Iwatsuki, S
Schade, R
Straub, W
Dekker, A
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1984
Date Type: Publication
Journal or Publication Title: Journal of Clinical Oncology
Volume: 2
Number: 6
Page Range: 637 - 642
DOI or Unique Handle: 10.1200/jco.1984.2.6.637
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0732-183X
Other ID: uls-drl:31735062115385, Starzl CV No. 575
Date Deposited: 08 Apr 2010 17:09
Last Modified: 02 Feb 2019 14:55
URI: http://d-scholarship.pitt.edu/id/eprint/3961

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