Lewis, JH and Bontempo, FA and Spero, JA and Ragni, MV and Starzl, TE
(1985)
Liver Transplantation in a Hemophiliac.
New England Journal of Medicine, 312 (18).
1189 - 1190.
ISSN 0028-4793
Abstract
To the Editor: A cure rather than a treatment has long been the goal of those caring for and those suffering from hemophilia. Encouraging results were obtained some years ago with the transplantation of normal livers into a dog with mild hemophilia1,2 and into four others with severe hemophilia.3 Two dogs given transplants survived more than 100 days and produced coagulation factor VIII in quantities sufficient to maintain normal levels. The first “cure” in a human being appears to have been achieved, at least temporarily, in a 15-year-old boy with hemophilia and severe chronic active hepatitis, who received a liver. © 1985, Massachusetts Medical Society. All rights reserved.
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