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Liver rejection and its differentiation from other causes of graft dysfunction.

Esquivel, CO and Jaffe, R and Gordon, RD and Iwatsuki, S and Shaw, BW and Starzl, TE (1985) Liver rejection and its differentiation from other causes of graft dysfunction. Semin Liver Dis, 5 (4). 369 - 374. ISSN 0272-8087

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Abstract

Numerous causes can lead to hepatic dysfunction following orthotopic liver transplantation. The most common cause is rejection, which is usually nonpreventable. The clinical presentation, time of onset, and even treatment are variable. Other causes, such as perioperative ischemic injury, vascular thrombosis, and complications of bile duct reconstruction may be preventable with good surgical technique. Infections can also be minimized by careful adjustment of immunotherapy, avoidance overimmunosuppression, and the judicious use of antibiotics. Hepatic dysfunction following orthotopic liver transplantation requires rapid assessment and proper treatment in order to prevent serious and possibly fatal complications.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Esquivel, CO
Jaffe, R
Gordon, RD
Iwatsuki, S
Shaw, BW
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: November 1985
Date Type: Publication
Journal or Publication Title: Semin Liver Dis
Volume: 5
Number: 4
Page Range: 369 - 374
DOI or Unique Handle: 10.1055/s-2008-1040634
Institution: University of Pittsburgh
Refereed: Yes
Uncontrolled Keywords: Bile Duct Diseases, Chemical and Drug Induced Liver Injury, Chickenpox, Child, Child, Preschool, Cytomegalovirus Infections, Female, Graft Rejection, Hemolysis, Hepatic Artery, Hepatitis, Viral, Human, Humans, Ischemia, Liver, Liver Transplantation, Postoperative Complications, Prednisolone, Thrombosis
ISSN: 0272-8087
Funders: NIADDK NIH HHS (AM-29961)
Other ID: uls-drl:31735062115864, Starzl CV No. 623
Date Deposited: 08 Apr 2010 17:10
Last Modified: 07 Aug 2020 10:55
URI: http://d-scholarship.pitt.edu/id/eprint/4009

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