Gordon, RD and Fung, JJ and Markus, B and Fox, I and Iwatsuki, S and Esquivel, CO and Tzakis, A and Todo, S and Starzl, TE
(1986)
The antibody crossmatch in liver transplantation.
Surgery, 100 (4).
705 - 715.
ISSN 0039-6060
Abstract
Six hundred sixty-seven first, second, and third orthotopic liver allografts in 520 patients were reviewed to determine the effects of recipient panel-reactive antibody (PRA) and donor-recipient antibody crossmatch on 2-year patient and liver allograft survival rates. Neither a high panel-reactive antibody nor a positive crossmatch for donor-specific preformed antibody was associated with decreased patient or liver allograft survival for primary grafts or retransplants. Two patients have been given kidney transplants immediately after a liver allograft from a donor with whom each patient had a initial strongly positive donor-specific antibody crossmatch. The liver apparently removed or neutralized circulating anti-donor antibody, since the renal allografts functioned promptly and did not experience hyperacute rejection.
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Item Type: |
Article
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Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID |
---|
Gordon, RD | | | | Fung, JJ | | | | Markus, B | | | | Fox, I | ijf5@pitt.edu | IJF5 | | Iwatsuki, S | | | | Esquivel, CO | | | | Tzakis, A | | | | Todo, S | | | | Starzl, TE | tes11@pitt.edu | TES11 | |
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Centers: |
Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute |
Date: |
30 December 1986 |
Date Type: |
Publication |
Journal or Publication Title: |
Surgery |
Volume: |
100 |
Number: |
4 |
Page Range: |
705 - 715 |
Institution: |
University of Pittsburgh |
Refereed: |
Yes |
ISSN: |
0039-6060 |
Other ID: |
uls-drl:31735062119593, Starzl CV No. 675 |
Date Deposited: |
08 Apr 2010 17:11 |
Last Modified: |
24 Jan 2018 04:55 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/4061 |
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