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Liver resection for metastatic colorectal cancer

Iwatsuki, S and Esquivel, CO and Gordon, RD and Starzl, TE (1986) Liver resection for metastatic colorectal cancer. Surgery, 100 (4). 804 - 810. ISSN 0039-6060

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From 1975 to 1985, 60 patients with isolated hepatic metastases from colorectal cancer were treated by 17 right trisegmentectomies, five left trisegmentectomies, 20 right lobectomies, seven left lobectomies, eight left lateral segmentectomies, and three nonanatomic wedge resections. The 1-month operative mortality rate was 0%. One- to 5-year actuarial survival rates of the 60 patients were 95%, 72%, 53%, 45%, and 45%, respectively. The survival rate after liver resection was the same when solitary lesions were compared with multiple lesions. However, none of the seven patients with four or more lesions survived 3 years. The interval after colorectal resection did not influence the survival rate after liver resection, and survival rates did not differ statistically when synchronous metastases were compared with metachronous tumors. A significant survival advantage of patients with Dukes' B primary lesions was noted when compared with Dukes' C and D lesions. The pattern of tumor recurrence after liver resection appeared to be systemic rather than hepatic. The patients who received systemic chemotherapy before clinical evidence of tumor recurrence after liver resection survived longer than those who did not.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Iwatsuki, S
Esquivel, CO
Gordon, RD
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1986
Date Type: Publication
Journal or Publication Title: Surgery
Volume: 100
Number: 4
Page Range: 804 - 810
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0039-6060
Other ID: uls-drl:31735062119700, Starzl CV No. 688
Date Deposited: 08 Apr 2010 17:11
Last Modified: 02 Feb 2019 13:56


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