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Choosing a pediatric recipient for orthotopic liver transplantation

Malatack, JJ and Schaid, DJ and Urbach, AH and Gartner, JC and Zitelli, BJ and Rockette, H and Fischer, J and Starzl, TE and Iwatsuki, S and Shaw, BW (1987) Choosing a pediatric recipient for orthotopic liver transplantation. The Journal of Pediatrics, 111 (4). 479 - 489. ISSN 0022-3476

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Abstract

Between March 3, 1981, and June 1, 1984, 216 children were evaluated for orthotopic liver transplantation. Of the 216 patients, 117 (55%) had recelved at least one liver transplant by June 1, 1985. Fifty-five (25%) died before transplantation. The 117 patients who received transplants were grouped according to severity of disease and degree of general decompensation at the time of transplantation. The severity of a patient's medical condition with the possible exception of deep hepatic coma, did not predict outcome following orthotopic liver transplantation. Seventy variables were assessed at the time of the evaluation. Twenty-three of the 70 variables were found to have prognostic significance with regard to death from progressive liver disease before transplantation. These 23 variables were Incorporated into a multivariate model to provide a means of determining the relative risk of death among pediatric patients with end-stage liver disease. This information may allow more informed selection of candidates awaiting liver transplantation. © 1987 The C. V. Mosby Company.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Malatack, JJ
Schaid, DJ
Urbach, AH
Gartner, JC
Zitelli, BJ
Rockette, H
Fischer, J
Starzl, TEtes11@pitt.eduTES11
Iwatsuki, S
Shaw, BW
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1987
Date Type: Publication
Journal or Publication Title: The Journal of Pediatrics
Volume: 111
Number: 4
Page Range: 479 - 489
DOI or Unique Handle: 10.1016/s0022-3476(87)80105-1
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0022-3476
Other ID: uls-drl:31735062119056, Starzl CV No. 711
Date Deposited: 08 Apr 2010 17:12
Last Modified: 13 Oct 2017 22:57
URI: http://d-scholarship.pitt.edu/id/eprint/4097

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