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Epstein-Barr Virus, Cytomegalovirus, and Other Viral Infections in Children After Liver Transplantatlon

Breinig, MK and Zitelli, B and Starzl, TE and Ho, M (1987) Epstein-Barr Virus, Cytomegalovirus, and Other Viral Infections in Children After Liver Transplantatlon. Journal of Infectious Diseases, 156 (2). 273 - 279. ISSN 0022-1899

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Abstract

We studied 51 consecutive pediatric patients for the frequency and morbidity of viral infections after liver transplantation. The incidence of primary (67%) and reactivation (48%) Epstein-Barr virus (EBV) infections and reactivation (88%) cytomegalovirus (CMV) infection was comparable to that seen in adult transplant recipients. However, fewer pediatric than adult transplant recipients experienced primary CMV infection (P `.01). Five (38%) of 13CMV infections were symptomatic and included hepatitis, pneumonitis, enteritis, and mononucleosis. Tho of 14 patients with primary EBV infection subsequently developed, at two months and two years after initial infection, an EBV-associated lymphoproliferative syndrome, and one of 10 patients with reactivated EBV infection developed a possible EBV-associated febrile encephalopathy. Other viruses causing infection in these children included herpes simplex virus, varicella-zoster virus, adenovirus, parainfluenza virus, respiratory syncytial virus, and rotavirus. © 1987 by The University of Chicago.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Breinig, MK
Zitelli, B
Starzl, TEtes11@pitt.eduTES11
Ho, Mmonto@pitt.eduMONTO
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1987
Date Type: Publication
Journal or Publication Title: Journal of Infectious Diseases
Volume: 156
Number: 2
Page Range: 273 - 279
DOI or Unique Handle: 10.1093/infdis/156.2.273
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0022-1899
Other ID: uls-drl:31735062119387, Starzl CV No. 744
Date Deposited: 08 Apr 2010 17:12
Last Modified: 13 Oct 2017 20:57
URI: http://d-scholarship.pitt.edu/id/eprint/4130

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