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Designing a Web-Based, Participatory Education Program Curriculum on Clinical Applications of Whole Genome Sequencing Utilizing Lessons Learned from Previous Participatory Genomics Courses

Gerow, Julia (2021) Designing a Web-Based, Participatory Education Program Curriculum on Clinical Applications of Whole Genome Sequencing Utilizing Lessons Learned from Previous Participatory Genomics Courses. Master's Thesis, University of Pittsburgh. (Unpublished)

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Background: Until recently, human genetics has primarily been used for research or targeted clinical testing. With the decreased cost and ease of access to genetic testing, there has been an expansion of the application of genetics to health and chronic disease states. The scalability of genetic testing has ushered in the era of Precision Medicine with integration of predictive modeling and genomics into health care. Historically, clinical genetics was limited geneticists supported by genetic counselors. However, with the massive expansion in access to genomic service, this prior model will not be able to meet the growing demand as genetics will now play a role in all areas of medicine. To integrate genetic services across the health care system, critical educational gaps will need to be addressed. Participatory genomic educational courses have been gaining popularity within genetics education because they include the opportunity for participants to undergo genetic testing and integrated applied learning modules. Test2Learn is a participatory education platform designed to teach adult learners about pharmacogenomics which was shown to increase the engagement of the learners by integrating the participatory element. Test2Learn has now been expanded to teach pharmacists, nurses, and primary care residents about pharmacogenomics and key precision medicine concepts. In the most recent iteration presented in this thesis, Test2Lean has been expanded to provide education of whole genome sequencing (WGS) to a broad array of clinicians and key opinion leaders.
Objective: Create an online, participatory WGS and Precision Medicine educational program delivered in the Test2Learn platform that is scalable for different populations.
Design: Develop a participatory educational program integrating the use of WGS data for adult, educated learners utilizing lessons learned from previous participatory genomics courses offered on the Test2Learn platform.
Assessment: Analyze pre- and post- program surveys to gather data to enhance the development of the Mellon Whole Genome Sequencing (MWGS) course.
Conclusion: Preliminary data in pilot programs shows that participation in the Test2Learn course significantly increased participants genetic knowledge and comfort level discussing genetic related issues with patients. Analysis of these results and current literature enhanced the creation of a novel, participatory WGS education program.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Gerow, Juliajgerow@pitt.edujgerow0000-0002-3658-6889
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairMassart,
Committee MemberDurst, Andreaadurst@pitt.eduadurst
Committee MemberBear, Toddtobst2@pitt.edutobst2
Date: 6 July 2021
Date Type: Publication
Defense Date: 20 May 2021
Approval Date: 6 July 2021
Submission Date: 30 June 2021
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Number of Pages: 193
Institution: University of Pittsburgh
Schools and Programs: School of Public Health > Human Genetics
Degree: MS - Master of Science
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: whole genome sequencing participatory education
Date Deposited: 06 Jul 2021 11:37
Last Modified: 06 Jul 2021 11:37


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