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Orthotopic liver transplantation for acute and subacute hepatic failure in adults

Peleman, RR and Gavaler, JS and Van Thiel, DH and Esquivel, C and Gordon, R and Iwatsuki, S and Starzl, TE (1987) Orthotopic liver transplantation for acute and subacute hepatic failure in adults. Hepatology, 7 (3). 484 - 489. ISSN 0270-9139

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Abstract

The role of liver transplantation in 29 patients with fulminant and subacute hepatic failure due to a variety of different causes was examined by comparing the outcome and a variety of “hospitalization” variables. Transplanted patients (n = 13) were more likely to survive (p < 0.05), were younger (p < 0.05) and spent more time in the hospital (p < 0.025) than did those who were not transplanted (n = 16). Despite spending a much longer time in the hospital, transplanted patients spent less time in the intensive care unit (p < 0.05) in coma (p < 0.01) and on a respirator (p < 0.01) than did those not transplanted. Most importantly, the survival rate for transplanted patients was significantly improved (p < 0.05) as compared to those not transplanted. We conclude that liver transplantation can be applied successfully to the difficult clinical problem of fulminant and subacute hepatic failure. Copyright © 1987 American Association for the Study of Liver Diseases

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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Peleman, RR
Gavaler, JS
Van Thiel, DH
Esquivel, C
Gordon, R
Iwatsuki, S
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1987
Date Type: Publication
Journal or Publication Title: Hepatology
Volume: 7
Number: 3
Page Range: 484 - 489
DOI or Unique Handle: 10.1002/hep.1840070312
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0270-9139
Other ID: uls-drl:31735062129295, Starzl CV No. 776
Date Deposited: 08 Apr 2010 17:13
Last Modified: 08 Jun 2021 10:55
URI: http://d-scholarship.pitt.edu/id/eprint/4162

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