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Effect of FK506 in experimental organ transplantation.

Todo, S and Murase, N and Ueda, Y and Podesta, L and ChapChap, P and Kahn, D and Okuda, K and Imventarza, O and Casavilla, A and Demetris, J (1988) Effect of FK506 in experimental organ transplantation. Transplant Proc, 20 (1 Supp). 215 - 219. ISSN 0041-1345

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FK506 is the most potent immunosuppressive agent known. Its toxicity is substantial in dogs, minor in rats, and unknown in subhuman primates. In small doses that are nontoxic even in dogs, it can be used in synergistic combination with cyclosporine, steroids, and presumably in other drugs.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Todo, S
Murase, N
Ueda, Y
Podesta, L
ChapChap, P
Kahn, D
Okuda, K
Imventarza, O
Casavilla, A
Demetris, J
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: February 1988
Date Type: Publication
Journal or Publication Title: Transplant Proc
Volume: 20
Number: 1 Supp
Page Range: 215 - 219
Institution: University of Pittsburgh
Refereed: Yes
Uncontrolled Keywords: Animals, Cyclosporins, Dogs, Drug Evaluation, Preclinical, Drug Therapy, Combination, Graft Rejection, Heart Transplantation, Immunosuppressive Agents, Kidney Diseases, Kidney Transplantation, Liver Transplantation, Prednisone, Pyridines, Rats, Rats, Inbred ACI, Rats, Inbred BN, Rats, Inbred Lew, Tacrolimus, Transplantation, Heterologous, Transplantation, Homologous
ISSN: 0041-1345
Funders: NIDDK NIH HHS (R01 DK029961-19), NIADDK NIH HHS (AM 29961)
Other ID: uls-drl:31735062129931, Starzl CV No. 842
Date Deposited: 08 Apr 2010 17:14
Last Modified: 06 Dec 2022 14:55


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