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Amelioration of normothermic canine liver ischemia with prostacyclin.

Todo, S and Yokoi, H and Podesta, L and ChapChap, P and Pan, C and Okuda, K and Kamiyama, Y and Demetris, J and Makowka, L and Iwatsuki, S (1988) Amelioration of normothermic canine liver ischemia with prostacyclin. Transplant Proc, 20 (1 Supp). 965 - 968. ISSN 0041-1345

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Abstract

A model of hepatic ischemia was developed in dogs using a pump-driven splanchnic-to-jugular vein bypass during crossclamping of the portal triad. An LD50 was established with three hours of ischemia. PGI2 given for one hour before the ischemic insult ameliorated the ischemic injury and increased survival.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Todo, S
Yokoi, H
Podesta, L
ChapChap, P
Pan, C
Okuda, K
Kamiyama, Y
Demetris, J
Makowka, L
Iwatsuki, S
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: February 1988
Date Type: Publication
Journal or Publication Title: Transplant Proc
Volume: 20
Number: 1 Supp
Page Range: 965 - 968
Institution: University of Pittsburgh
Refereed: Yes
Uncontrolled Keywords: Animals, Dogs, Epoprostenol, Ischemia, Liver
ISSN: 0041-1345
Funders: NIDDK NIH HHS (R01 DK029961-19), NIADDK NIH HHS (AM 29961)
Other ID: uls-drl:31735062129949, Starzl CV No. 843
Date Deposited: 08 Apr 2010 17:14
Last Modified: 14 Oct 2017 05:57
URI: http://d-scholarship.pitt.edu/id/eprint/4229

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