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A Descriptive Pilot Study of Emergency Department Usage in Progressive Supranuclear Palsy, and a Literature Review of the Pathophysiology and Epidemiology of the Disease

Bartel, William Philip (2022) A Descriptive Pilot Study of Emergency Department Usage in Progressive Supranuclear Palsy, and a Literature Review of the Pathophysiology and Epidemiology of the Disease. Master Essay, University of Pittsburgh.

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Abstract

Progressive nuclear palsy (PSP) is a lethal neurodegenerative disease, characterized by the deposition of 4-repeat (4R)-Tau in the brain. Few therapeutic options exist. Public health efforts to reduce the morbidity and mortality of this disease are currently undermined by our limited understanding of the disease and its pathogenesis. While information on healthcare resource utilization and the economic impact of PSP is generally lacking, the sparse data that exists suggests that patients with PSP utilize the emergency department (ED) an inordinate amount. Anecdotal clinical experience suggests that falls and fall related injuries are likely responsible for the majority of ED utilization in PSP. However, the literature on ED utilization in PSP is limited and somewhat outdated. The overall aim of this pilot study was to describe the usage of the ED by patients with PSP, to better characterize the impact of specific causes of morbidity in the disease. Increased knowledge of how and why the ED is used in PSP could improve public health efforts targeted at reducing morbidity by highlighting where better preventative measures need to be developed. Our findings suggest that falls are indeed the most common and significant reason that PSP patients seek emergency medical care.


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Details

Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Unpublished
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Bartel, William Philipwpb17@pi.eduwpb17
Contributors:
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairFinegold, David N.dnf@pitt.edudnfUNSPECIFIED
Committee Co-ChairBurton, Edward A.eab25@pitt.edueab25UNSPECIFIED
Date: 16 May 2022
Date Type: Completion
Submission Date: 27 April 2022
Access Restriction: 2 year -- Restrict access to University of Pittsburgh for a period of 2 years.
Number of Pages: 71
Institution: University of Pittsburgh
Schools and Programs: School of Public Health > Multidisciplinary MPH
Degree: MPH - Master of Public Health
Thesis Type: Master Essay
Refereed: Yes
Uncontrolled Keywords: Progressive Supranuclear Palsy, PSP, Emergency Department Utilization, Falls, Fall Related Injuries, Tauopathy, Neurodegenerative Disease
Date Deposited: 16 May 2022 19:13
Last Modified: 16 May 2022 19:13
URI: http://d-scholarship.pitt.edu/id/eprint/42793

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