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The Interlinked Rising Epidemic of Insufficient Sleep and Diabetes Mellitus

Chattu, Vijay and Chattu, Soosanna and Burman, Deepa and Spence, David and Pandi-Perumal, Seithikurippu (2019) The Interlinked Rising Epidemic of Insufficient Sleep and Diabetes Mellitus. Healthcare, 7 (1). p. 37. ISSN 2227-9032

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For healthy existence, humans need to spend one-third of their time sleeping. Any qualitative or quantitative disturbances in sleep would result in an increased prevalence of obesity, metabolic disorders, diabetes, cardiovascular diseases, and hypertension. The paper aims to highlight the growing global problem of insufficient sleep and its significant impact on the rising incidence of diabetes mellitus. An extensive literature search was done in all major databases for “insufficient sleep” and “Diabetes Mellitus” for this review. Shorter (<6 h) and longer (>9 h) durations of sleep have been adversely related to insulin resistance. Though the relation between insufficient sleep and diabetes mellitus is more or less understood, little is known about how oversleeping or hypersomnia (10–12 h) increases the risk of diabetes. The relationship between sleep disturbances and diabetes is dual-sided, as chronic sleep disturbances would elevate the risk of developing insulin resistance, while diabetes would worsen the quality of sleep. Both the qualitative and quantitative disturbances in sleep significantly increase the risk of developing diabetes, which is supported by numerous community-based and hospital-based epidemiological studies discussed in this review. Obstructive sleep apnea is one of the most common sleep disorders and is characterized by chronic intermittent hypoxia and increased sympathetic activity, thus leading to a higher prevalence of diabetes. Sleep therapy may serve as a low-cost method for fighting against the rising epidemic of diabetes.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Chattu, Vijay0000-0001-9840-8335
Chattu, Soosanna0000-0002-2365-7836
Burman, Deepadeb120@pitt.edu0000-0002-6549-7076
Spence, David0000-0002-1664-6960
Pandi-Perumal, Seithikurippu0000-0002-8686-7259
Date: 5 March 2019
Date Type: Publication
Journal or Publication Title: Healthcare
Volume: 7
Number: 1
Publisher: MDPI AG
Page Range: p. 37
DOI or Unique Handle: 10.3390/healthcare7010037
Schools and Programs: School of Medicine > Pediatrics
Refereed: Yes
Uncontrolled Keywords: diabetes mellitus, insufficient sleep, insufficient sleep syndrome, metabolic syndrome, obesity, obstructive sleep apnea, sleep-disordered breathing
ISSN: 2227-9032
Official URL:
Article Type: Review
Date Deposited: 18 May 2022 16:41
Last Modified: 18 May 2022 16:41


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