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Experience with resection of primary hepatic malignancy

Iwatsuki, S and Starzl, TE (1989) Experience with resection of primary hepatic malignancy. Surgical Clinics of North America, 69 (2). 315 - 322. ISSN 0039-6109

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Our experience with hepatic resection for 106 primary hepatic malignancies has been summarized as a part of a total experience with 411 hepatic resections for various indications. The operative mortality rate (death within a month) was 8.5 per cent in treating primary hepatic malignancy, which is significantly higher than that of treating hepatic metastases (0 of 123 resections). Overall operative mortality of 411 hepatic resection was 3.2 per cent. A high operative risk was noted in patients with gross cirrhosis, trauma, abscess, and large malignant tumors. The 1-, 3-, and 5-year survival rates of patients with primary hepatic malignancy were 68.5 per cent, 45.1 per cent, and 31.9 per cent, respectively. Survival rates of patients with fibrolamellar hepatocellular carcinoma were significantly higher than those of patients with nonfibrolamellar hepatocellular carcinoma. Eighteen patients survived more than 5 years after hepatic resection, 14 of whom had been treated by trisegmentectomy. The most extensive partial hepatectomy, such as right and left trisegmentectomy rather than extended lobectomies, should be used to remove massive tumors with adequate tumor-free margins.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Iwatsuki, S
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1989
Date Type: Publication
Journal or Publication Title: Surgical Clinics of North America
Volume: 69
Number: 2
Page Range: 315 - 322
DOI or Unique Handle: 10.1016/s0039-6109(16)44788-2
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0039-6109
Other ID: uls-drl:31735062130764, Starzl CV No. 926
Date Deposited: 08 Apr 2010 17:15
Last Modified: 02 Feb 2019 13:57


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