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Transplantation of multiple abdominal viscera.

Starzl, TE and Rowe, MI and Todo, S and Jaffe, R and Tzakis, A and Hoffman, AL and Esquivel, C and Porter, KA and Venkataramanan, R and Makowka, L (1989) Transplantation of multiple abdominal viscera. JAMA, 261 (10). 1449 - 1457. ISSN 0098-7484

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Two children with the short-gut syndrome and secondary liver failure were treated with evisceration and transplantation en bloc of the stomach, small intestine, colon, pancreas, and liver. The first patient died perioperatively, but the second lived for more than 6 months before dying of an Epstein-Barr virus-associated lymphoproliferative disorder that caused biliary obstruction and lethal sepsis. There was never evidence of graft rejection or of graft-vs-host disease in the long-surviving child. The constituent organs of the homograft functioned and maintained their morphological integrity throughout the 193 days of survival.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Starzl, TEtes11@pitt.eduTES11
Rowe, MI
Todo, S
Jaffe, R
Tzakis, A
Hoffman, AL
Esquivel, C
Porter, KA
Venkataramanan, Rrv@pitt.eduRV
Makowka, L
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 10 March 1989
Date Type: Publication
Journal or Publication Title: JAMA
Volume: 261
Number: 10
Page Range: 1449 - 1457
Institution: University of Pittsburgh
Refereed: Yes
Uncontrolled Keywords: Animals, Autopsy, Child, Child, Preschool, Cyclosporins, Female, Humans, Intestines, Liver, Lymphoproliferative Disorders, Pancreas, Postoperative Care, Postoperative Complications, Swine, Viscera
ISSN: 0098-7484
Other ID: uls-drl:31735062130897, Starzl CV No. 940
Date Deposited: 08 Apr 2010 17:16
Last Modified: 12 Oct 2017 09:56


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