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Raw data for Lefever et al., 2022 PMID: 35736460

Lefever, Daniel (2022) Raw data for Lefever et al., 2022 PMID: 35736460. [Dataset] (Unpublished)

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Available under License Creative Commons Attribution No Derivatives.

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This data download includes the raw data for Lefever DE, Miedel MT, Pei F, DiStefano JK, Debiasio R, Shun TY, Saydmohammed M, Chikina M, Vernetti LA, Soto-Gutierrez A, Monga SP, Bataller R, Behari J, Yechoor VK, Bahar I, Gough A, Stern AM, Taylor DL. A Quantitative Systems Pharmacology Platform Reveals NAFLD Pathophysiological States and Targeting Strategies. Metabolites. 2022 Jun 7;12(6):528. doi: 10.3390/metabo12060528. PMID: 35736460; PMCID: PMC9227696.

Processed data and supplementary data files are available at: The R analysis code for this study is available at:

Total unzipped size of this data package is 1.83 GB.


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Item Type: Dataset
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Lefever, Daniellefeverde@gmail.comdel530000-0003-2274-1881
Date: 7 June 2022
DOI or Unique Handle:
Uncontrolled Keywords: CMap; MAFLD; MPS; NAFLD; NASH; QSP; connectivity map; drug combinations; drug discovery; drug repurposing; fibrosis; liver; lobular inflammation; metabolic-associated fatty liver disease; microphysiology systems; network proximity; non-alcoholic fatty liver disease; non-alcoholic steatohepatitis; quantitative systems pharmacology; steatosis; targeting disease states
Official URL:
Related URLs:
Funders: 1UG3TR003289-01-NIH/NCATS, 4UH3DK119973-03-NIH/NIDDK, 4UH3DK119973-03-NIH/NIDDK, S10OD12269-NIH, U24TR002632-NIH/NCATS, 5U01 TR002383-03-NIH/NCATS, R01 DK097160-NIH/NIDDK, R01 DK088231-NIH/NIDDK, P41 GM103712 NIH/NIGMS, PO1 DK096990 NIH/NIDDK, 1P30DK120531-01
Type of Data: Mixed
Copyright Holders: NA
Date Deposited: 06 Mar 2023 17:29
Last Modified: 06 Mar 2023 17:29


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