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Parent Perceptions of Emergent RhD-Positive Blood Transfusion in Children

Morgan, Katrina (2023) Parent Perceptions of Emergent RhD-Positive Blood Transfusion in Children. Master Essay, University of Pittsburgh.

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RhD-negative blood products are in chronic short supply leading to renewed interest in utilizing RhD-positive blood products for emergency transfusions. This study assessed parental perceptions of emergency RhD-positive blood use in children.
A survey on the tolerance of the D-alloimmunization risk on the part of parents/guardians of their daughters 17 years old was conducted at four level 1 pediatric hospitals.
In total, 621 parents/guardians were approached of whom 378/621 (61%) completed the survey in its entirety and were included in the analysis. Respondents were mostly females [295/378 (78%)], White [242/378 (64%)], had some college education [217/378 (57%)] and less than $60,000 annual income [193/378 (51%)]. Respondents had a total of 547 female children. Most children’s ABO [320/547 (59%)] and RhD type [348/547 (64%)] were not known by their parents; of children with known RhD type, 58/186 (31%) were RhD-negative. When the risk of harm to a future fetus was given as 0-6%, more than 80% of respondents indicated they were likely to accept RhD-mismatched blood transfusions on behalf of their daughter in a life-threatening situation. The rate of willingness to accept emergent RhD-mismatched blood transfusions significantly increased as the potential survival benefit of the transfusion increased.
Most parents were willing to accept RhD-positive blood products on behalf of their daughter in an emergency situation. Further discussions and evidence-based guidelines on transfusing RhD-positive blood products to RhD-unknown females in emergency settings are needed.


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Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Morgan, Katrinamorgankm@pitt.edumorgankm0000-0002-0307-0472
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairFinegold, Daviddnf@pitt.edudnfUNSPECIFIED
Committee MemberLeeper, Christineleepercm@upmc.eduUNSPECIFIED0000-0002-8561-8760
Centers: Other Centers, Institutes, Offices, or Units > Center for Global Health
Date: 17 May 2023
Date Type: Completion
Access Restriction: 1 year -- Restrict access to University of Pittsburgh for a period of 1 year.
Number of Pages: 31
Institution: University of Pittsburgh
Schools and Programs: School of Public Health > Multidisciplinary MPH
Degree: MPH - Master of Public Health
Thesis Type: Master Essay
Refereed: Yes
Uncontrolled Keywords: RhD-positive blood, whole blood; pediatric trauma; D-alloimmunization; hemolytic disease of the fetus and newborn
Date Deposited: 17 May 2023 14:04
Last Modified: 17 May 2023 14:04


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