Morgan, Katrina
(2023)
Parent Perceptions of Emergent RhD-Positive Blood Transfusion in Children.
Master Essay, University of Pittsburgh.
Abstract
Background
RhD-negative blood products are in chronic short supply leading to renewed interest in utilizing RhD-positive blood products for emergency transfusions. This study assessed parental perceptions of emergency RhD-positive blood use in children.
Methods
A survey on the tolerance of the D-alloimmunization risk on the part of parents/guardians of their daughters 17 years old was conducted at four level 1 pediatric hospitals.
Results
In total, 621 parents/guardians were approached of whom 378/621 (61%) completed the survey in its entirety and were included in the analysis. Respondents were mostly females [295/378 (78%)], White [242/378 (64%)], had some college education [217/378 (57%)] and less than $60,000 annual income [193/378 (51%)]. Respondents had a total of 547 female children. Most children’s ABO [320/547 (59%)] and RhD type [348/547 (64%)] were not known by their parents; of children with known RhD type, 58/186 (31%) were RhD-negative. When the risk of harm to a future fetus was given as 0-6%, more than 80% of respondents indicated they were likely to accept RhD-mismatched blood transfusions on behalf of their daughter in a life-threatening situation. The rate of willingness to accept emergent RhD-mismatched blood transfusions significantly increased as the potential survival benefit of the transfusion increased.
Conclusion
Most parents were willing to accept RhD-positive blood products on behalf of their daughter in an emergency situation. Further discussions and evidence-based guidelines on transfusing RhD-positive blood products to RhD-unknown females in emergency settings are needed.
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Details
| Item Type: |
Other Thesis, Dissertation, or Long Paper
(Master Essay)
|
| Status: |
Unpublished |
| Creators/Authors: |
|
| Contributors: |
| Contribution | Contributors Name | Email | Pitt Username | ORCID  |
|---|
| Committee Chair | Finegold, David | dnf@pitt.edu | dnf | UNSPECIFIED | | Committee Member | Leeper, Christine | leepercm@upmc.edu | UNSPECIFIED | 0000-0002-8561-8760 |
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| Centers: |
Other Centers, Institutes, Offices, or Units > Center for Global Health |
| Date: |
17 May 2023 |
| Date Type: |
Completion |
| Access Restriction: |
1 year -- Restrict access to University of Pittsburgh for a period of 1 year. |
| Number of Pages: |
31 |
| Institution: |
University of Pittsburgh |
| Schools and Programs: |
School of Public Health > Multidisciplinary MPH |
| Degree: |
MPH - Master of Public Health |
| Thesis Type: |
Master Essay |
| Refereed: |
Yes |
| Uncontrolled Keywords: |
RhD-positive blood, whole blood; pediatric trauma; D-alloimmunization; hemolytic disease of the fetus and newborn |
| Date Deposited: |
17 May 2023 14:04 |
| Last Modified: |
17 May 2023 14:04 |
| URI: |
http://d-scholarship.pitt.edu/id/eprint/44191 |
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