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Relationship Between Sleep and Depression in Individuals with Post-Stroke Aphasia

Zarbis, Kaitlin (2023) Relationship Between Sleep and Depression in Individuals with Post-Stroke Aphasia. Master's Thesis, University of Pittsburgh. (Unpublished)

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Background: Many stroke survivors experience issues with their sleep following their stroke, such as difficulty falling asleep and staying asleep, or decreased sleep quality. Difficulties with sleep can also be related to and cause mental health obstacles, such as depression; at the same time, poor mental health can exacerbate and cause difficulties with sleep. It is very likely that people with
aphasia (PWA) experience sleep impairments or disorders, which can impact their course of recovery and their mental health; however, there is a dearth of research that explores the relationship between sleep and depression in individuals with post-stroke aphasia. This study seeks to consider the association between self-reported sleep disturbance and self-reported depression
symptoms while accounting for demographic, stroke, and language variables. Furthermore, this study provides preliminary findings exploring the correlations between self-reported sleep disturbance, sleep related impairments, fatigue, and depression in individuals with chronic poststroke aphasia, while also commenting on the potential feasibility of specific self-report sleep questionnaires within the post-stroke aphasia population.

Procedures: This study includes an analysis of 72 PWA who completed measures of aphasia severity, depression, and sleep. Furthermore, this study includes seven PWA that were administered subtests of the Comprehensive Aphasia Test; the Patient Reported Outcomes Measurement Information System (PROMIS) – Sleep Disturbance (SD), – Sleep Related Impairment (SRI), and – Fatigue; and the Patient Health Questionnaire – 8 (PHQ-8).

Results: The only statistically significant and meaningful predictor of PHQ-8 responses in the multiple regression model was PROMIS-SD Short Form 8a responses. Furthermore, positive correlations were revealed between self-reported sleep disturbance and depression (though modest), self-reported sleep related impairment and depression, self-reported fatigue and sleep disturbance, self-reported fatigue and sleep related impairment, and self-reported sleep disturbance and sleep related impairment. There was a weak negative correlation found between self-reported fatigue and depression.

Conclusions: Given this preliminary data, it is important to consider sleep, fatigue, and depression as potential factors impacting rehabilitation and overall quality of life in the post-stroke aphasia population.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Zarbis, Kaitlinkaz94@pitt.edukaz94
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Thesis AdvisorDickey, Michael
Committee MemberWallace, Sarah
Committee MemberHula,
Committee MemberHunting Pompon,
Date: 6 June 2023
Date Type: Publication
Defense Date: 17 March 2023
Approval Date: 6 June 2023
Submission Date: 30 March 2023
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Number of Pages: 78
Institution: University of Pittsburgh
Schools and Programs: School of Health and Rehabilitation Sciences > Communication Science and Disorders
Degree: MS - Master of Science
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: aphasia, sleep, depression, fatigue, stroke
Date Deposited: 06 Jun 2023 13:52
Last Modified: 06 Jun 2023 13:52


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