Mieles, L and Todo, S and Tzakis, A and Starzl, TE
(1990)
Treatment of upper abdominal malignancies with organ cluster procedures.
Clinical Transplantation, 4 (2).
63 - 67.
ISSN 0902-0063
Abstract
Upper abdominal exenteration for upper abdominal malignancies was carried out in 15 patients with removal of the liver, spleen, pancreas, duodenum, all or part of the stomach, proximal jejunum and ascending and transverse colon. Organ replacement was with the liver, pancreas and duodenum plus, in some cases, a short segment of jejunum. Eleven of the 15 patients survived for more than 4 months; 2 died, after 6 1/2 and 10 months, of recurrent tumor. Of the 9 patients who are surviving after 6 1/2 to 14 months, recurrent tumor is suspected in only 1 and proven in none. Four patients with sarcomas and carcinoid tumors (2 each) have had no recurrences. The other 5 survivors had duct cell cancers (3 examples), a cholangiocarcinoma (1 example), and a hepatoma (1 example). The experience so far supports further cautious trials with this drastic cancer operation.
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