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An Update on Nipah Virus: Past Lessons, Current Efforts, & Future Goals

Chapa, Larisa Garza (2023) An Update on Nipah Virus: Past Lessons, Current Efforts, & Future Goals. Master Essay, University of Pittsburgh.

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Nipah virus (NiV) is an emerging infectious disease first identified in 1998 in Malaysia. Over the course of the quarter century since the disease emerged, multiple identified spillovers have occurred in Malaysia, India, and Bangladesh, with case fatality rates ranging from 40% to 100%. While technologies and surveillance have improved since the identification of Nipah virus, it is notable that the characterizations and locations of the outbreaks have broadened. Pteropus bats are the reservoir host of NiV; the disease commonly presents as myalgia and fever, progressing to fatal encephalitis. Monoclonal antibodies and the use of mRNA vaccines are currently being explored, but there is no approved NiV vaccine or specified treatment for infected patients. It is important from a public health perspective to understand the potential in this emerging infectious disease, as preventative measures should be undertaken on local, state, federal, and global scales to identify, diagnose, and prevent the spread of NiV through the use of multiple interdisciplinary collaborative preventative and outbreak control efforts.


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Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Chapa, Larisa Garzalgc23@pitt.edulgc23
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairMartinson, Jeremyjmartins@pitt.edujmartinsUNSPECIFIED
Committee MemberSalter, Cynthiacys6@pitt.educys6UNSPECIFIED
Date: 19 May 2023
Date Type: Completion
Number of Pages: 50
Institution: University of Pittsburgh
Schools and Programs: School of Public Health > Infectious Diseases and Microbiology
Degree: MPH - Master of Public Health
Thesis Type: Master Essay
Refereed: Yes
Date Deposited: 19 May 2023 13:47
Last Modified: 19 May 2023 13:47


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