Sun, Jiabao
(2023)
A Comparison of Inferior Turbinate Hypertrophy in Pediatric Patients with Cleft Lip and Palate.
Master's Thesis, University of Pittsburgh.
(Unpublished)
Abstract
Background: Nasal septum deviation can cause compensatory inferior turbinate hypertrophy (ITH) on the unobstructed side. Patients with unilateral cleft lip and palate (UCLP) are prone to develop compensatory ITH on the non-cleft side due to nasal septum deviation. However, the prevalence of ITH in patients with bilateral complete cleft lip and palate (BCLP) and SMCP is still unclear. Patients with cleft lip and palate have been found to have more severe nasal septum deviation than patients without.
Objective: The primary aim of this study was to compare the prevalence of ITH in patients with BCLP, UCLP and submucous cleft palate (SMCP) using lateral cephalometric radiographs. The secondary aim was to compare the prevalence of ITH in patients with complete cleft, i.e. BCLP and UCLP, and in healthy controls.
Methods: Lateral cephalometric radiographs of pediatric patients with BCLP, UCLP, and SMCP treated at UPMC Children’s Hospital of Pittsburgh Orthodontics Department were examined to determine the prevalence of ITH in each group. Lateral cephalometric radiographs from the Bolton Brush Growth study (AAOF) were examined to determine the prevalence of ITH in healthy population. Ten percent of the radiographs were reexamined 1 month after the initial examination to determine intra-rater reliability. Chi square test was used to determine if there was a significant difference in the prevalence of ITH among the groups with cleft, and between patients with complete cleft and the AAOF. Regression analysis was performed to determine the odds ratio of ITH among the cleft groups, and the odds ratio of ITH in patients with complete cleft compared to the AAOF group. Kappa test was used to calculate the intra-rater reliability.
Results: No statistically significant difference was found in the prevalence of ITH among the cleft groups before and after adjusting for confounders. The prevalence of ITH was significantly higher in patients with complete cleft than the AAOF subjects.
Conclusions: Patients with BCLP, UCLP or SMCP have the same risk of developing ITH. Patients with complete cleft are more likely to develop ITH than healthy subjects.
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Details
| Item Type: |
University of Pittsburgh ETD
|
| Status: |
Unpublished |
| Creators/Authors: |
|
| ETD Committee: |
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| Date: |
1 July 2023 |
| Date Type: |
Publication |
| Defense Date: |
23 May 2023 |
| Approval Date: |
1 July 2023 |
| Submission Date: |
26 May 2023 |
| Access Restriction: |
No restriction; Release the ETD for access worldwide immediately. |
| Number of Pages: |
35 |
| Institution: |
University of Pittsburgh |
| Schools and Programs: |
School of Dental Medicine > Dental Science |
| Degree: |
MDS - Master of Dental Science |
| Thesis Type: |
Master's Thesis |
| Refereed: |
Yes |
| Uncontrolled Keywords: |
craniofacial cleft |
| Date Deposited: |
01 Jul 2023 13:32 |
| Last Modified: |
01 Jul 2023 13:32 |
| URI: |
http://d-scholarship.pitt.edu/id/eprint/44901 |
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