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Nonobstructing Colonic Dilatation and Colon Perforations Following Renal Transplantation

Koneru, B and Selby, R and O'hair, DP and Tzakis, AG and Hakala, TR and Starzl, TE (1990) Nonobstructing Colonic Dilatation and Colon Perforations Following Renal Transplantation. Archives of Surgery, 125 (5). 610 - 613. ISSN 0004-0010

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Abstract

Nonobstructing colonic dilatation has not been commonly reported following renal transplantation, and colon perforations carry a high morbidity and mortality in this population. During a 7-year period, nonobstructing colonic dilatation developed in 13 adults 1 to 13 days after renal transplantation. Twelve (92%) of the 13 had poorly functioning allografts. Five (83%) of the 6 with and 2 (29%) of the 7 without colonoscopy had resolution of nonobstructing colonic dilatation. Of the seven right-sided colon perforations during this period, six were associated with nonobstructing colonic dilatation. An additional 4 patients had diverticular perforations in the left colon. Of a total of 11 patients with colon perforation, 7 had surgery within 24 hours of the perforation and 6 (86%) of these survived. Only 1 (25%) of the 4 having surgery more than 24 hours later survived. Six of the survivors retained functioning allografts. Nonobstructing colonic dilatation seems to be a potential complication of poor graft function after renal transplantation, and colonoscopy is effective in its treatment. In patients with colon perforations, early surgery and reduced immunosuppression are essential in decreasing mortality. © 1990, American Medical Association. All rights reserved.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Koneru, B
Selby, R
O'hair, DP
Tzakis, AG
Hakala, TR
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1990
Date Type: Publication
Journal or Publication Title: Archives of Surgery
Volume: 125
Number: 5
Page Range: 610 - 613
DOI or Unique Handle: 10.1001/archsurg.1990.01410170056012
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0004-0010
Other ID: uls-drl:31735062116706, Starzl CV No. 1116
Date Deposited: 08 Apr 2010 17:19
Last Modified: 13 Oct 2017 17:55
URI: http://d-scholarship.pitt.edu/id/eprint/4502

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