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Incidence and treatment of rejection episodes in primary orthotopic liver transplantation under FK 506.

Jain, AB and Fung, JJ and Todo, S and Alessiani, M and Takaya, S and Abu-Elmagd, K and Tzakis, A and Starzl, TE (1991) Incidence and treatment of rejection episodes in primary orthotopic liver transplantation under FK 506. Transplant Proc, 23 (1 Pt 2). 928 - 930. ISSN 0041-1345

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Abstract

FK 506 therapy with low doses of steroids was adequate to control rejection in most liver recipients. Rejection episodes were readily reversed with single IV doses of methylprednisone or hydrocortisone. Short courses of OKT3 (3 to 5 days 5-10 mL) controlled severe rejections. The rate of retransplantation directly due to rejection was low (1.6%). There was a limited need for steroids either early or out to 6 to 12 months.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Jain, AB
Fung, JJ
Todo, S
Alessiani, M
Takaya, S
Abu-Elmagd, K
Tzakis, A
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: February 1991
Date Type: Publication
Journal or Publication Title: Transplant Proc
Volume: 23
Number: 1 Pt 2
Page Range: 928 - 930
Institution: University of Pittsburgh
Refereed: Yes
Uncontrolled Keywords: Anti-Bacterial Agents, Antibodies, Monoclonal, Graft Rejection, Humans, Hydrocortisone, Immunosuppression, Immunosuppressive Agents, Liver Diseases, Liver Transplantation, Methylprednisolone, Muromonab-CD3, Survival Analysis, Tacrolimus
ISSN: 0041-1345
Funders: NIDDK NIH HHS (R01 DK029961-19), NIDDK NIH HHS (DK 29961)
Other ID: uls-drl:31735062117290, Starzl CV No. 1177
Date Deposited: 08 Apr 2010 17:20
Last Modified: 13 Oct 2017 22:55
URI: http://d-scholarship.pitt.edu/id/eprint/4563

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