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Predicting the Impact and Trends of SARS-CoV-2 on the Respiratory Viral Season in Pittsburgh Using Interpretable Machine Learning Forecast Models: A Quality Improvement (QI) Retrospective Study

Puri, Shikha (2024) Predicting the Impact and Trends of SARS-CoV-2 on the Respiratory Viral Season in Pittsburgh Using Interpretable Machine Learning Forecast Models: A Quality Improvement (QI) Retrospective Study. Master Essay, University of Pittsburgh.

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Abstract

This Quality Improvement (QI) project utilizes predictive modeling to understand the dynamics of the COVID-19 pandemic, particularly examining the interaction with the respiratory virus season (RVS) encompassing Respiratory Syncytial Virus (RSV), Influenza, and SARS-CoV-2. This project seeks to determine whether COVID-19 will remain an additional burden on laboratories or diminish, making it another respiratory virus in the RVS. The analysis is from October 2015 to December 2023, examining incidence and ICD-10 cases from UPMC Shadyside and Presbyterian hospitals in Pittsburgh. This analysis compared pre- and post-COVID-19 periods, revealing evolving burdens on laboratories and hospitals. Our exploratory data analysis (EDA) visualizes the seasonal trends of the respiratory viruses, highlighting a shift in typical RVS patterns coinciding with the onset of SARS-CoV-2. Simple and Seasonal Naïve forecasting models provide baseline insights, while ARIMA and SARIMA models offer more advanced prediction techniques, acknowledging data complexities post-COVID-19. Despite SARIMA's superior performance, challenges arise due to limited post-pandemic data, emphasizing the need for continued data collection. The public health implications for our research are for proactive healthcare planning and understanding COVID-19's trajectory as a potentially endemic virus. Future endeavors will focus on continued data collection to refine the predictive models, create effective resource allocation strategies, and relieve the healthcare burden for potential future pandemics.


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Details

Item Type: Other Thesis, Dissertation, or Long Paper (Master Essay)
Status: Unpublished
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Puri, Shikhapuri.shikha@gmail.comshp79
Contributors:
ContributionContributors NameEmailPitt UsernameORCID
Committee ChairMartinson, Jeremyjmartins@pitt.edujmartinsUNSPECIFIED
Committee MemberPasculle, Williampasculleaw@upmc.eduUNSPECIFIEDUNSPECIFIED
Date: 21 May 2024
Date Type: Completion
Submission Date: 25 April 2024
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Number of Pages: 52
Institution: University of Pittsburgh
Schools and Programs: School of Public Health > Infectious Diseases and Microbiology
Degree: MPH - Master of Public Health
Thesis Type: Master Essay
Refereed: Yes
Uncontrolled Keywords: Predictive Model, Forecast, Forecasting model, ARIMA, SARIMA, Naive Forecasting, COVID-19, SARS-Cov-2, RSV, Influenza, Incidence, ICD-10, Pittsburgh, UPMC
Date Deposited: 21 May 2024 14:54
Last Modified: 21 May 2024 14:54
URI: http://d-scholarship.pitt.edu/id/eprint/46311

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