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Pancreatic complications following orthotopic liver transplantation

Yanaga, K and Shimada, M and Gordon, RD and Tzakis, AG and Makowka, L and Marsh, JW and Stieber, AC and Todo, S and Iwatsuki, S and Starzi, TE (1992) Pancreatic complications following orthotopic liver transplantation. Clinical Transplantation, 6 (2). 126 - 130. ISSN 0902-0063

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Abstract

During fiscal year 1986, 40 out of 196 patients (21%) developed hyperamylasemia following orthotopic liver transplantation. The placement of a retropancreatic aortohepatic arterial interposition graft was associated with hyperamylasemia (p < 0.025). Eight patients (20%) developed clinically significant acute pancreatitis and its sequelae; abscesses and pseudocysts each in 2. Pancreatitis was attributable to the retropancreatic arterial graft in 4, viral infection in 2 and obstruction of the pancreatic duct in 1 patient. All 4 patients with arterial graft-related pancreatitis exhibited poor graft function immediately postoperatively, of whom 2 required retransplantation - both of which failed to function. Five patients died (63%); 2 from primary graft non-function, 2 due to sepsis and 1 from systemic cytomegalovirus infection. We conclude that acute pancreatitis after liver transplantation is a life-threatening complication which is often associated with graft non-function.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Yanaga, K
Shimada, M
Gordon, RD
Tzakis, AG
Makowka, L
Marsh, JW
Stieber, AC
Todo, S
Iwatsuki, S
Starzi, TE
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1992
Date Type: Publication
Journal or Publication Title: Clinical Transplantation
Volume: 6
Number: 2
Page Range: 126 - 130
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0902-0063
Other ID: uls-drl:31735062111608, Starzl CV No. 1365
Date Deposited: 08 Apr 2010 17:23
Last Modified: 05 Feb 2019 11:55
URI: http://d-scholarship.pitt.edu/id/eprint/4751

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