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Kaposi's sarcoma in two primary liver allograft recipients occurring under FK506 immunosuppression

Kadry, Z and Bronsther, O and Van Thiel, DH and Randhawa, P and Fung, JJ and Starzl, TE (1993) Kaposi's sarcoma in two primary liver allograft recipients occurring under FK506 immunosuppression. Clinical Transplantation, 7 (2). 188 - 194. ISSN 0902-0063

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Abstract

Of 1463 liver allograft recipients receiving the combination of FK506 and steroids as their primary immunosuppressive regimen, 2 patients developed Kaposi's sarcoma. Although previously described as a complication of organ transplantation, this is the first case report of Kaposi's sarcoma occurring in association with the macrolide immunosuppressive agent FK506. A discussion of the clinical presentation and course of Kaposi's sarcoma in these 2 patients, as well as a review of the past literature on Kaposi's sarcoma in organ transplant recipients, emphasizes the therapeutic difficulties encountered. Kaposi's sarcoma is also compared to lymphoproliferative disorders, another well-recognized complication of immunosuppression, highlighting the differences between these two entities.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Kadry, Z
Bronsther, O
Van Thiel, DH
Randhawa, P
Fung, JJ
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 28 May 1993
Date Type: Publication
Journal or Publication Title: Clinical Transplantation
Volume: 7
Number: 2
Page Range: 188 - 194
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0902-0063
Other ID: uls-drl:31735062112259, Starzl CV No. 1438
Date Deposited: 08 Apr 2010 17:24
Last Modified: 02 Feb 2019 13:57
URI: http://d-scholarship.pitt.edu/id/eprint/4824

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