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Intestinal transplantation in children under FK 506 immunosuppression

Tzakis, AG and Todo, S and Reyes, J and Nour, B and Abu-Elmagd, K and Selby, R and Casavilla, A and Kocoshis, S and Demetris, AJ and Yunis, E and Van Thiel, DH and Starzl, TE (1993) Intestinal transplantation in children under FK 506 immunosuppression. Journal of Pediatric Surgery, 28 (8). 1040 - 1043. ISSN 0022-3468

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Intestinal transplantation, solitary (n = 3) or in combination with the liver (n = 7), was performed in 10 pediatric patients with intestinal failure. The liver was only replaced if there was liver failure and portal hypertension. Immunosuppression was based on FK 506. Two patients died, one of graft-versus-host disease and one of lymphoproliferative disease. One patient was still in the intensive care unit 1 month posttransplantation due to perioperative complications. The function of the intestinal grafts in the remaining patients is normal. All nutrition and medications including immunosuppression are being administered enterally. This series indicates that small bowel transplantation, alone or in combination with the liver, is feasible in pediatric patients. © 1993.


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Item Type: Article
Status: Published
CreatorsEmailPitt UsernameORCID
Tzakis, AG
Todo, S
Reyes, J
Nour, B
Abu-Elmagd, K
Selby, R
Casavilla, A
Kocoshis, S
Demetris, AJ
Yunis, E
Van Thiel, DH
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1993
Date Type: Publication
Journal or Publication Title: Journal of Pediatric Surgery
Volume: 28
Number: 8
Page Range: 1040 - 1043
DOI or Unique Handle: 10.1016/0022-3468(93)90514-l
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0022-3468
Other ID: uls-drl:31735062112309, Starzl CV No. 1441
Date Deposited: 08 Apr 2010 17:24
Last Modified: 27 Jan 2019 02:55


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