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The relationship of systemic hemodynamics and oxygen consumption to early allograft failure after liver transplantation.

Takaya, S and Nonami, T and Selby, R and Doyle, H and Murray, G and Kramer, D and Kang, Y and Starzl, TE (1993) The relationship of systemic hemodynamics and oxygen consumption to early allograft failure after liver transplantation. Transpl Int, 6 (2). 73 - 76. ISSN 0934-0874

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Abstract

The early postoperative hemodynamic data of 88 patients who underwent primary liver transplantation between July 1989 and October 1990 at the University Health Center of Pittsburgh were analyzed to establish the relationship of systemic hemodynamics and oxygen consumption to perioperative allograft function. The 15 patients whose allografts failed within the 1st month following transplantation were designated as group 1, while 73 patients who retained adequate graft function constituted group 2. Although the cardiac index and oxygen delivery did not differ significantly between the groups, group 1 consistently demonstrated a lower mean arterial pressure, oxygen consumption, arteriovenous oxygen content difference, and arterial ketone body ratio. The etiology of reduced oxygen consumption in group 1 patients is speculative, but the data support the notion that oxygen consumption is a useful, predictive indicator for liver allograft function after transplantation.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Takaya, S
Nonami, T
Selby, R
Doyle, H
Murray, G
Kramer, D
Kang, Y
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date: March 1993
Date Type: Publication
Journal or Publication Title: Transpl Int
Volume: 6
Number: 2
Page Range: 73 - 76
DOI or Unique Handle: 10.1007/bf00336648
Institution: University of Pittsburgh
Refereed: Yes
Uncontrolled Keywords: Adolescent, Adult, Aged, Blood Pressure, Female, Graft Rejection, Hemodynamics, Humans, Ketone Bodies, Liver, Liver Transplantation, Male, Middle Aged, Oxygen Consumption, Transplantation, Homologous
ISSN: 0934-0874
Funders: NIDDK NIH HHS (R01 DK029961-19), NIDDK NIH HHS (DK 29961)
Other ID: uls-drl:31735062113356, Starzl CV No. 1544
Date Deposited: 08 Apr 2010 17:26
Last Modified: 26 Mar 2022 12:55
URI: http://d-scholarship.pitt.edu/id/eprint/4930

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