Ricordi, C and Tzakis, AG and Zeevi, A and Rybka, WB and Demetris, AJ and Fontes, PAC and Nalesnik, MA and Trucco, M and Ukah, FO and Ball, ED and Mullen, EE and Marino, IR and Fung, JJ and Starzl, TE
(1994)
Reversal of graft-versus-host disease with infusion of autologous bone marrow.
Cell Transplantation, 3 (2).
187 - 192.
ISSN 0963-6897
Abstract
Graft-versus-host disease (GVHD) remains a major complication of bone marrow transplantation. This report describes reversal of GVHD by infusion of stored recipient bone marrow following combined liver-bone marrow allotransplantation. Graft-versus-host disease developed at the end of the first postoperative week. The skin involvement progressively spread to approximately 80% of the body surface and was not affected by modification of the immunosuppressive treatment. On the 42nd and 43rd postoperative day 1.23 × 108 and 1.6 × 108 autologous bone marrow cells per kg of recipient body weight were infused. The skin rush began to dramatically improve and resolved within 2 wk from the autologous marrow infusion. Autologous bone marrow storage previous to allogeneic bone marrow transplantation for tolerance induction could constitute a safety net in case of occurrence of GVHD. © 1994.
Share
Citation/Export: |
|
Social Networking: |
|
Details
Item Type: |
Article
|
Status: |
Published |
Creators/Authors: |
Creators | Email | Pitt Username | ORCID  |
---|
Ricordi, C | | | | Tzakis, AG | | | | Zeevi, A | | | | Rybka, WB | | | | Demetris, AJ | | | | Fontes, PAC | | | | Nalesnik, MA | nalesnik@pitt.edu | NALESNIK | | Trucco, M | mnt@pitt.edu | MNT | | Ukah, FO | | | | Ball, ED | | | | Mullen, EE | | | | Marino, IR | | | | Fung, JJ | | | | Starzl, TE | tes11@pitt.edu | TES11 | |
|
Centers: |
Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute |
Date: |
1 January 1994 |
Date Type: |
Publication |
Journal or Publication Title: |
Cell Transplantation |
Volume: |
3 |
Number: |
2 |
Page Range: |
187 - 192 |
DOI or Unique Handle: |
10.1177/096368979400300207 |
Institution: |
University of Pittsburgh |
Refereed: |
Yes |
ISSN: |
0963-6897 |
Other ID: |
uls-drl:31735062125640, Starzl CV No. 1606 |
Date Deposited: |
08 Apr 2010 17:27 |
Last Modified: |
22 Jun 2021 14:56 |
URI: |
http://d-scholarship.pitt.edu/id/eprint/4992 |
Metrics
Monthly Views for the past 3 years
Plum Analytics
Altmetric.com
Actions (login required)
 |
View Item |