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The 11-year Pittsburgh experience with liver transplantation for hepatocellular carcinoma: 1981-1991

Van Thiel, DH and Carr, B and Iwatsuki, S and Selby, RR and Fung, JJ and Starzl, TE (1993) The 11-year Pittsburgh experience with liver transplantation for hepatocellular carcinoma: 1981-1991. Journal of Surgical Oncology, 53 (SUPPL.). 78 - 82. ISSN 0022-4790

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Abstract

Experience with liver transplantation over a period of 11 years at the University of Pittsburgh is presented. The application of liver transplantation to cases of hepatocellular carcinoma has changed considerably over this 11-year period with the sequential introduction of adjuvant and, more recently, neoadjuvant chemotherapy. Results with the combination of chemotherapy plus surgery appear to be better than results with either agent alone. Moreover, the early results with neoadjuvant therapy appear to be better than those achieved with adjuvant therapy. As a result of this experience, conceptual changes in the approach to the problem of hepatic cancer and the role of both chemotherapy and liver transplantation in its management have changed at the University of Pittsburgh. These changes are identified and discussed.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Van Thiel, DH
Carr, B
Iwatsuki, S
Selby, RR
Fung, JJ
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 1993
Date Type: Publication
Journal or Publication Title: Journal of Surgical Oncology
Volume: 53
Number: SUPPL.
Page Range: 78 - 82
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0022-4790
Other ID: uls-drl:31735062125806, Starzl CV No. 1614
Date Deposited: 08 Apr 2010 17:27
Last Modified: 02 Feb 2019 13:55
URI: http://d-scholarship.pitt.edu/id/eprint/5000

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