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Role of estrogens and epidermal growth factor in hepatocellular carcinoma (HCC)

Francavilla, A and Panella, C and Amoruso, A and Giangaspero, A and Gennari, L and Mazzaferro, V and Colella, G and Van Thiel, DH and Starzl, TE (1991) Role of estrogens and epidermal growth factor in hepatocellular carcinoma (HCC). Digestive Diseases and Sciences, 36 (9). 1299 - 1302. ISSN 0163-2116

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Abstract

Estrogen (E) and epidermal growth factors (EGF) receptors were assayed in the liver of nine patients with hepatocellular carcinoma (HCC). Total E and nuclear E receptors were decreased significantly in neoplastic tissue as compared to the levels found in surrounding nonneoplastic tissue. The EGF receptor was decreased also in neoplastic tissue. On the basis of binding data, a decrease in the number but not in affinity of both the E and EGF receptors was found. © 1991 Plenum Publishing Corporation.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Francavilla, A
Panella, C
Amoruso, A
Giangaspero, A
Gennari, L
Mazzaferro, V
Colella, G
Van Thiel, DH
Starzl, TEtes11@pitt.eduTES11
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 September 1991
Date Type: Publication
Journal or Publication Title: Digestive Diseases and Sciences
Volume: 36
Number: 9
Page Range: 1299 - 1302
DOI or Unique Handle: 10.1007/bf01307526
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0163-2116
Other ID: uls-drl:31735062125145, Starzl CV No. 1665
Date Deposited: 08 Apr 2010 17:28
Last Modified: 30 Oct 2017 23:56
URI: http://d-scholarship.pitt.edu/id/eprint/5051

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