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Transplantation tolerance from a historical perspective

Starzl, TE and Zinkernagel, RM (2001) Transplantation tolerance from a historical perspective. Nature Reviews Immunology, 1 (3). 233 - 239. ISSN 1474-1733

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Abstract

Although transplantation immunology as a distinctive field began with the development of experimental models that showed the feasibility of bone marrow transplantation, organ engraftment was accomplished first in humans, and was thought for many years to occur by drastically different mechanisms. Here, we present our view of the concepts of allograft acceptance and acquired tolerance from a historical perspective, and attempt to amalgamate them into simple and unifying rules that might guide improvements in clinical therapy.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Starzl, TEtes11@pitt.eduTES11
Zinkernagel, RM
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 January 2001
Date Type: Publication
Journal or Publication Title: Nature Reviews Immunology
Volume: 1
Number: 3
Page Range: 233 - 239
DOI or Unique Handle: 10.1038/35105088
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 1474-1733
Article Type: Review
Other ID: uls-drl:31735062120732, Starzl CV No. 2167
Date Deposited: 08 Apr 2010 17:37
Last Modified: 26 May 2018 11:55
URI: http://d-scholarship.pitt.edu/id/eprint/5553

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