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Cold heparinized lactated ringers with procaine (HeLP) preservation fluid in 266 living donor kidney transplantations

Tan, HP and Vyas, D and Basu, A and Randhawa, P and Shah, N and Donaldson, J and Marcos, A and Simmons, RL and Starzl, TE and Shapiro, R (2007) Cold heparinized lactated ringers with procaine (HeLP) preservation fluid in 266 living donor kidney transplantations. Transplantation, 83 (8). 1134 - 1136. ISSN 0041-1337

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Abstract

Since the 1960s simple inexpensive cold lactated Ringers with additives has been used for short-term cold preservation of kidneys from living donors. We performed 266 living donor kidney transplantations from January 22, 2003 to October 30, 2006. Donor allografts were recovered laparoscopically and flushed with cold heparin, lactated Ringer's and procaine (HeLP) solution. Warm and cold ischemic times were typically <45 min and <90 min, respectively. The mean follow up was 21.6±12.2 months. There was no delayed graft function. Actuarial 1-year patient and graft survival were 98.6% and 98.1%, respectively. The creatinine at 1 year was 1.46±0.51 mg/dL. The cumulative incidences of acute cellular rejection at 6, 12, 18, and 24 months were 3.0%, 7.1%, 10.2%, and 11.7%. There were no identifiable side effects attributed to the HeLP solution. This study documents the effectiveness of cold HeLP as a flushing and short-term preservation fluid for living donor kidney transplantation with excellent results and significant cost benefit because of its low cost. © 2007 Lippincott Williams & Wilkins, Inc.


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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Tan, HP
Vyas, D
Basu, A
Randhawa, P
Shah, N
Donaldson, J
Marcos, A
Simmons, RL
Starzl, TEtes11@pitt.eduTES11
Shapiro, R
Centers: Other Centers, Institutes, or Units > Thomas E. Starzl Transplantation Institute
Date: 1 April 2007
Date Type: Publication
Journal or Publication Title: Transplantation
Volume: 83
Number: 8
Page Range: 1134 - 1136
DOI or Unique Handle: 10.1097/01.tp.0000260408.47857.61
Institution: University of Pittsburgh
Refereed: Yes
ISSN: 0041-1337
Other ID: uls-drl:31735062121508, Starzl CV No. 2242
Date Deposited: 08 Apr 2010 17:38
Last Modified: 04 Feb 2019 15:58
URI: http://d-scholarship.pitt.edu/id/eprint/5628

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