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Association Between Daytime and Nighttime Ambulatory Blood Pressure and Carotid Atherosclerosis: The Influence of Physical Activity

Garcia, Jeanette Madeline (2011) Association Between Daytime and Nighttime Ambulatory Blood Pressure and Carotid Atherosclerosis: The Influence of Physical Activity. Master's Thesis, University of Pittsburgh. (Unpublished)

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The purpose of this study was to examine the associations between daytime and nighttime ambulatory blood pressure (ABP) on carotid IMT when controlling for daytime physical activity (PA) in a sample of 201 healthy older adults (mean age 66.9 yrs, 49.8% females) who were part of the 6 year follow-up of the Pittsburgh Healthy Heart Project (PHHP). Daytime ABP and nighttime ABP were assessed every 45 minutes over a period of 3 days and 2 nights. Physical activity was measured by a wrist accelerometer, a waist accelerometer, and a self-report measure of physical activity. Regression analysis was used to analyze the association of daytime and nighttime ABP with carotid IMT and to determine the type of PA measure (wrist, waist, or self-report), and the time interval (1, 5, 10, 15 minutes prior to ABP) that has the greatest influence on daytime ABP. Results showed that PA 1 minute (wrist) and 10 minutes (waist) prior to ABP assessment accounted for 9% of the variance in daytime ABP. When entered separately into a regression model, both daytime SBP (F(1,194)=6.33, p=.01) and nighttime SBP (F(1,194)=6.46, p=.01) significantly predicted IMT. When entered simultaneously into the model, both daytime SBP(F(1,193)=1.81, p=.18) and nighttime SBP(F(1,193)=1.94, p=.17) lost their significance. However, after adjusting for PA, daytime SBP (F(1,193)=3.47, p=.06) was a marginally stronger predictor of IMT than nighttime SBP. This finding supports the specific prognostic importance of daytime ABP and, to that extent, may support work on a greater understanding of the daytime variables that uniquely influence daytime ABP as potential correlates of CVD risk.


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Item Type: University of Pittsburgh ETD
Status: Unpublished
CreatorsEmailPitt UsernameORCID
Garcia, Jeanette Madelinejmg12@pitt.eduJMG12
ETD Committee:
TitleMemberEmail AddressPitt UsernameORCID
Committee ChairKamarck, Thomastkam@pitt.eduTKAM
Committee MemberMatthews, KarenmatthewsKA@upmc.eduXYOO
Committee MemberManuck, Stevemanuck@pitt.eduMANUCK
Date: 6 June 2011
Date Type: Completion
Defense Date: 18 April 2011
Approval Date: 6 June 2011
Submission Date: 21 April 2011
Access Restriction: No restriction; Release the ETD for access worldwide immediately.
Institution: University of Pittsburgh
Schools and Programs: Dietrich School of Arts and Sciences > Psychology
Degree: MS - Master of Science
Thesis Type: Master's Thesis
Refereed: Yes
Uncontrolled Keywords: ambultory blood pressure; cardiovascular disease; physical activity
Other ID:, etd-04212011-212823
Date Deposited: 10 Nov 2011 19:40
Last Modified: 19 Dec 2016 14:35


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